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Identifying multi-locus chromatin contacts in human cells using tethered multiple 3C.

BMC genomics | 2015

Several recently developed experimental methods, each an extension of the chromatin conformation capture (3C) assay, have enabled the genome-wide profiling of chromatin contacts between pairs of genomic loci in 3D. Especially in complex eukaryotes, data generated by these methods, coupled with other genome-wide datasets, demonstrated that non-random chromatin folding correlates strongly with cellular processes such as gene expression and DNA replication.

Pubmed ID: 25887659 RIS Download

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Associated grants

  • Agency: European Research Council, International
    Id: 280032
  • Agency: NHGRI NIH HHS, United States
    Id: U41 HG007000
  • Agency: NIGMS NIH HHS, United States
    Id: R01 GM09031

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GM12878 (tool)

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Cell line GM12878 is a Transformed cell line with a species of origin Homo sapiens (Human)

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Cell line Hep-G2 is a Cancer cell line with a species of origin Homo sapiens (Human)

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HUVEC-C (tool)

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Cell line HUVEC-C is a Finite cell line with a species of origin Homo sapiens

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