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The tumour-promoting receptor tyrosine kinase, EphB4, regulates expression of integrin-β8 in prostate cancer cells.

BMC cancer | 2015

The EphB4 receptor tyrosine kinase is overexpressed in many cancers including prostate cancer. The molecular mechanisms by which this ephrin receptor influences cancer progression are complex as there are tumor-promoting ligand-independent mechanisms in place as well as ligand-dependent tumor suppressive pathways.

Pubmed ID: 25886373 RIS Download

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Agilent Feature Extraction Software (tool)

RRID:SCR_014963

Software that automatically reads and processes up to 100 raw microarray image files. The software finds and places microarray grids, rejects outlier pixels, accurately determines feature intensities and ratios, flags outlier pixels, and calculates statistical confidences.

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22Rv1 (tool)

RRID:CVCL_1045

Cell line 22Rv1 is a Cancer cell line with a species of origin Homo sapiens (Human)

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LNCaP (tool)

RRID:CVCL_0395

Cell line LNCaP is a Cancer cell line with a species of origin Homo sapiens (Human)

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