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Identification of a microRNA signature associated with risk of distant metastasis in nasopharyngeal carcinoma.

Oncotarget | 2015

Despite significant improvement in locoregional control in the contemporary era of nasopharyngeal carcinoma (NPC) treatment, patients still suffer from a significant risk of distant metastasis (DM). Identifying those patients at risk of DM would aid in personalized treatment in the future. MicroRNAs (miRNAs) play many important roles in human cancers; hence, we proceeded to address the primary hypothesis that there is a miRNA expression signature capable of predicting DM for NPC patients.

Pubmed ID: 25738365 RIS Download

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Associated grants

  • Agency: Canadian Institutes of Health Research, Canada

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NanoStringNorm (tool)

RRID:SCR_003382

A set of tools for normalizing, diagnostics and visualization of NanoString nCounter data. Key features include an extensible environment for method comparison and new algorithm development, integrated gene and sample diagnostics, and facilitated downstream statistical analysis.

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