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Genome of the avirulent human-infective trypanosome--Trypanosoma rangeli.

Patrícia Hermes Stoco | Glauber Wagner | Carlos Talavera-Lopez | Alexandra Gerber | Arnaldo Zaha | Claudia Elizabeth Thompson | Daniella Castanheira Bartholomeu | Débora Denardin Lückemeyer | Diana Bahia | Elgion Loreto | Elisa Beatriz Prestes | Fábio Mitsuo Lima | Gabriela Rodrigues-Luiz | Gustavo Adolfo Vallejo | José Franco da Silveira Filho | Sérgio Schenkman | Karina Mariante Monteiro | Kevin Morris Tyler | Luiz Gonzaga Paula de Almeida | Mauro Freitas Ortiz | Miguel Angel Chiurillo | Milene Höehr de Moraes | Oberdan de Lima Cunha | Rondon Mendonça-Neto | Rosane Silva | Santuza Maria Ribeiro Teixeira | Silvane Maria Fonseca Murta | Thais Cristine Marques Sincero | Tiago Antonio de Oliveira Mendes | Turán Peter Urmenyi | Viviane Grazielle Silva | Wanderson Duarte DaRocha | Björn Andersson | Alvaro José Romanha | Mário Steindel | Ana Tereza Ribeiro de Vasconcelos | Edmundo Carlos Grisard
PLoS neglected tropical diseases | 2014

Trypanosoma rangeli is a hemoflagellate protozoan parasite infecting humans and other wild and domestic mammals across Central and South America. It does not cause human disease, but it can be mistaken for the etiologic agent of Chagas disease, Trypanosoma cruzi. We have sequenced the T. rangeli genome to provide new tools for elucidating the distinct and intriguing biology of this species and the key pathways related to interaction with its arthropod and mammalian hosts.

Pubmed ID: 25233456 RIS Download

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This is a list of tools and resources that we have found mentioned in this publication.


InterProScan (tool)

RRID:SCR_005829

Software package for functional analysis of sequences by classifying them into families and predicting presence of domains and sites. Scans sequences against InterPro's signatures. Characterizes nucleotide or protein function by matching it with models from several different databases. Used in large scale analysis of whole proteomes, genomes and metagenomes. Available as Web based version and standalone Perl version and SOAP Web Service.

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SMART (tool)

RRID:SCR_005026

Software tool for identification and annotation of genetically mobile domains and analysis of domain architectures.

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PHYLIP (tool)

RRID:SCR_006244

A free package of software programs for inferring phylogenies (evolutionary trees). The source code is distributed (in C), and executables are also distributed. In particular, already-compiled executables are available for Windows (95/98/NT/2000/me/xp/Vista), Mac OS X, and Linux systems. Older executables are also available for Mac OS 8 or 9 systems.

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InterPro (tool)

RRID:SCR_006695

Service providing functional analysis of proteins by classifying them into families and predicting domains and important sites. They combine protein signatures from a number of member databases into a single searchable resource, capitalizing on their individual strengths to produce a powerful integrated database and diagnostic tool. This integrated database of predictive protein signatures is used for the classification and automatic annotation of proteins and genomes. InterPro classifies sequences at superfamily, family and subfamily levels, predicting the occurrence of functional domains, repeats and important sites. InterPro adds in-depth annotation, including GO terms, to the protein signatures. You can access the data programmatically, via Web Services. The member databases use a number of approaches: # ProDom: provider of sequence-clusters built from UniProtKB using PSI-BLAST. # PROSITE patterns: provider of simple regular expressions. # PROSITE and HAMAP profiles: provide sequence matrices. # PRINTS provider of fingerprints, which are groups of aligned, un-weighted Position Specific Sequence Matrices (PSSMs). # PANTHER, PIRSF, Pfam, SMART, TIGRFAMs, Gene3D and SUPERFAMILY: are providers of hidden Markov models (HMMs). Your contributions are welcome. You are encouraged to use the ''''Add your annotation'''' button on InterPro entry pages to suggest updated or improved annotation for individual InterPro entries.

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CAP3 Sequence Assembly Program (tool)

RRID:SCR_007250

This form allows you to assemble a set of contiguous sequences (contigs) with the CAP3 program. The CAP3 program has a capability to clip 5'' and 3'' low-quality regions of reads. It uses base quality values in computation of overlaps between reads, construction of multiple sequence alignments of reads, and generation of consensus sequences. The program also uses forward-reverse constraints to correct assembly errors and link contigs. Results of CAP3 on four BAC data sets are presented. The performance of CAP3 was compared with that of PHRAP on a number of BAC data sets. PHRAP often produces longer contigs than CAP3 whereas CAP3 often produces fewer errors in consensus sequences than PHRAP. It is easier to construct scaffolds with CAP3 than with PHRAP on low-pass data with forward-reverse constraints. Sponsors: This project was supported by NIH Grant R01HG01502-02 from NHGRI. Keywords: CAP3, Program, Form, Computation, DNA, Dataset, Database, Program,

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TRAP (tool)

RRID:SCR_009002

Software tool for determining a regression model of quantitative or binary trait variation when the number of possible genetic predictors is very large, considering only a moderate number of predictors at one time, using unrelated or family data. (entry from Genetic Analysis Software)

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TBLASTN (tool)

RRID:SCR_011822

Tool to search translated nucleotide databases using a protein query.

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TBLASTX (tool)

RRID:SCR_011823

A web-based tool used to search translated nucleotide databases using a translated nucleotide query.

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Newbler (tool)

RRID:SCR_011916

A software package for de novo DNA sequence assembly.

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TreeView (tool)

RRID:SCR_013503

Software to graphically browse results of clustering and other analyses from Cluster.

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RepeatScout (tool)

RRID:SCR_014653

Algorithm used to identify de novo repeat families in newly sequenced genomes. Repeat libraries for C. briggsae, M. muscles (X chromosome), R. novegicus (X chromosome), armadillo, H. sapiens (X chromosome), and various other mammals created using RepeatScout are available on the main site.

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Vero (tool)

RRID:CVCL_0059

Cell line Vero is a Spontaneously immortalized cell line with a species of origin Chlorocebus sabaeus

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