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Publication

Cardiac dysfunction and peri-weaning mortality in malonyl-coenzyme A decarboxylase (MCD) knockout mice as a consequence of restricting substrate plasticity.

Journal of molecular and cellular cardiology | 2014

Inhibition of malonyl-coenzyme A decarboxylase (MCD) shifts metabolism from fatty acid towards glucose oxidation, which has therapeutic potential for obesity and myocardial ischemic injury. However, ~40% of patients with MCD deficiency are diagnosed with cardiomyopathy during infancy.

Pubmed ID: 25066696 RIS Download

Research resources used in this publication

None found

Additional research tools detected in this publication

Antibodies used in this publication

None found

Associated grants

  • Agency: British Heart Foundation, United Kingdom
    Id: PG/05/141/20098
  • Agency: British Heart Foundation, United Kingdom
    Id: RG/13/8/30266
  • Agency: British Heart Foundation, United Kingdom
    Id: PG/08/080/25726
  • Agency: Wellcome Trust, United Kingdom
  • Agency: British Heart Foundation, United Kingdom
    Id: RG/07/003/23133
  • Agency: Wellcome Trust, United Kingdom
    Id: 90532/Z/09/Z

Publication data is provided by the National Library of Medicine ® and PubMed ®. Data is retrieved from PubMed ® on a weekly schedule. For terms and conditions see the National Library of Medicine Terms and Conditions.

This is a list of tools and resources that we have found mentioned in this publication.

C57BL/6J (tool)

RRID:IMSR_JAX:000664

Mus musculus with name C57BL/6J from IMSR.

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