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Vaccines against human HER2 prevent mammary carcinoma in mice transgenic for human HER2.

Breast cancer research : BCR | 2014

The availability of mice transgenic for the human HER2 gene (huHER2) and prone to the development of HER2-driven mammary carcinogenesis (referred to as FVB-huHER2 mice) prompted us to study active immunopreventive strategies targeting the human HER2 molecule in a tolerant host.

Pubmed ID: 24451168 RIS Download

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