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Low cerebral blood flow is associated with lower memory function in metabolic syndrome.

Obesity (Silver Spring, Md.) | 2013

Metabolic syndrome (MetS)--a cluster of cardiovascular risk factors--is linked with cognitive decline and dementia. However, the brain changes underlying this link are presently unknown. In this study, we tested the relationship between MetS, cerebral blood flow (CBF), white matter hyperintensity burden, and gray matter (GM) volume in cognitively healthy late middle-aged adults. Additionally, the extent to which MetS was associated with cognitive performance was assessed.

Pubmed ID: 23687103 RIS Download

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Associated grants

  • Agency: NICHD NIH HHS, United States
    Id: P30 HD003352
  • Agency: NCATS NIH HHS, United States
    Id: UL1 TR000427
  • Agency: NIA NIH HHS, United States
    Id: R01 AG027161
  • Agency: NCRR NIH HHS, United States
    Id: 1UL1RR025011
  • Agency: NIA NIH HHS, United States
    Id: P50 AG033514
  • Agency: NCRR NIH HHS, United States
    Id: UL1 RR025011
  • Agency: NIA NIH HHS, United States
    Id: R01 AG021155

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MarsBaR region of interest toolbox for SPM (tool)

RRID:SCR_009605

A toolbox for SPM which provides routines for region of interest analysis. Features include region of interest definition, combination of regions of interest with simple algebra, extraction of data for regions with and without SPM preprocessing (scaling, filtering), and statistical analyses of ROI data using the SPM statistics machinery.

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SPM (tool)

RRID:SCR_007037

Software package for analysis of brain imaging data sequences. Sequences can be a series of images from different cohorts, or time-series from same subject. Current release is designed for analysis of fMRI, PET, SPECT, EEG and MEG.

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