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ATP-binding cassette (ABC) transporter expression and localization in sea urchin development.

Developmental dynamics : an official publication of the American Association of Anatomists | 2012

ATP-binding cassette (ABC) transporters are membrane proteins that regulate intracellular concentrations of myriad compounds and ions. There are >100 ABC transporter predictions in the Strongylocentrotus purpuratus genome, including 40 annotated ABCB, ABCC, and ABCG "multidrug efflux" transporters. Despite the importance of multidrug transporters for protection and signaling, their expression patterns have not been characterized in deuterostome embryos.

Pubmed ID: 22473856 RIS Download

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Associated grants

  • Agency: NICHD NIH HHS, United States
    Id: K99 HD058070
  • Agency: NICHD NIH HHS, United States
    Id: R00 HD058070
  • Agency: NICHD NIH HHS, United States
    Id: R00 HD058070-05
  • Agency: NICHD NIH HHS, United States
    Id: HD058070

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