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NPY controls fear conditioning and fear extinction by combined action on Y₁ and Y₂ receptors.

British journal of pharmacology | 2012

Neuropeptide Y (NPY) and its receptors have been implicated in the control of emotional-affective processing, but the mechanism is unclear. While it is increasingly evident that stimulation of Y₁ and inhibition of Y₂ receptors produce prominent anxiolytic and antidepressant effects, the contribution of the individual NPY receptor subtypes in the acquisition and extinction of learned fear are unknown.

Pubmed ID: 22289084 RIS Download

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Associated grants

  • Agency: Austrian Science Fund FWF, Austria
    Id: S 10204

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RRID:IMSR_JAX:000664

Mus musculus with name C57BL/6J from IMSR.

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