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The prolyl isomerase Pin1 modulates development of CD8+ cDC in mice.

PloS one | 2012

Pin1 has previously been described to regulate cells that participate in both innate and adaptive immunity. Thus far, however, no role for Pin1 has been described in modulating conventional dendritic cells, innate antigen presenting cells that potently activate naïve T cells, thereby bridging innate and adaptive immune responses.

Pubmed ID: 22238658 RIS Download

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Associated grants

  • Agency: NCI NIH HHS, United States
    Id: R01 CA082845
  • Agency: NCI NIH HHS, United States
    Id: CA082846

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