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Receptor-mediated gene delivery by folic acid-modified stearic acid-grafted chitosan micelles.

International journal of nanomedicine | 2011

Cationic polymers have been accepted as effective nonviral vectors for gene delivery with low immunogenicity unlike viral vectors. However, the lack of organ or cell specificity sometimes hampers their application and the modification of polymeric vectors has also shown successful improvements in achieving cell-specific targeting delivery and in promoting intracellular gene transfer efficiency.

Pubmed ID: 21845046 RIS Download

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