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Protein kinase C inhibition ameliorates functional endothelial insulin resistance and vascular smooth muscle cell hypersensitivity to insulin in diabetic hypertensive rats.

Cardiovascular diabetology | 2011

Insulin resistance, diabetes, and hypertension are considered elements of metabolic syndrome which is associated with vascular dysfunction. We investigated whether inhibition of protein kinase C (PKC) would affect vascular function in diabetic hypertensive (DH) rats.

Pubmed ID: 21635764 RIS Download

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Associated grants

  • Agency: NHLBI NIH HHS, United States
    Id: R01 HL-084529

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SD (tool)

RRID:RGD_70508

Rattus norvegicus with name SD from RGD.

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