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Plasma kallikrein mediates retinal vascular dysfunction and induces retinal thickening in diabetic rats.

Diabetes | 2011

Plasma kallikrein (PK) has been identified in vitreous fluid obtained from individuals with diabetic retinopathy and has been implicated in contributing to retinal vascular dysfunction. In this report, we examined the effects of PK on retinal vascular functions and thickness in diabetic rats.

Pubmed ID: 21444925 RIS Download

Associated grants

  • Agency: NEI NIH HHS, United States
    Id: R01 EY019029
  • Agency: NHLBI NIH HHS, United States
    Id: HL-090132
  • Agency: NEI NIH HHS, United States
    Id: EY-19029
  • Agency: NIDDK NIH HHS, United States
    Id: DK-36836
  • Agency: NIDDK NIH HHS, United States
    Id: P30 DK036836
  • Agency: NHLBI NIH HHS, United States
    Id: R43 HL090132

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This is a list of tools and resources that we have found mentioned in this publication.


Joslin Diabetes Center Bioinformatics and Biostatistics Core (tool)

RRID:SCR_015092

Core that offers support for data-driven projects related to basic, clinical and translational research, with a particular emphasis on diabetes. The core aims to ensure that researchers take advantage of the most modern and robust methods available in the field of Bioinformatics and Biostatistics.

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Joslin Diabetes Center Flow Cytometry Core Facility (tool)

RRID:SCR_009878

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 27,2023. Core that provides cell sorting and flow cytometry services. Specific services include cell analysis, large object sorting,magnetic cell enrichment, and automatic cell counting.

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Joslin Diabetes Center Advanced Microscopy Core Facility (tool)

RRID:SCR_009875

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 27,2023. Core that provides services for performing specific morphological procedures, providing training and access to equipment, maintaining the specialized microscopes, and giving advice and interpretation.

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Joslin Diabetes Center Animal Physiology Core Facility (tool)

RRID:SCR_009876

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 27,2023. Core that provides technically advanced physiological evaluation of metabolism in diabetes, obesity, and their associated complications in rodents for DRC investigators and outside users. It also provides training of investigators and trainees in several physiological procedures.

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Joslin Diabetes Center Advanced Genomics and Genetics Core Facility (tool)

RRID:SCR_009873

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 27,2023. Core that provides services for genetic and genomic analysis, including DNA extraction from blood, access to DNA collections from the Core?s repository, SNP genotyping, and support for gene expression studies based on both high-density oligonucleotide arrays and real-time quantitative PCR.

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Joslin Diabetes Center Induced Pluripotent Stem Cell Core (tool)

RRID:SCR_015120

Core that maintains a centralized facility for the generation and propagation of reprogrammed iPS cells for use in molecular and cellular pathologies underlying diabetes and its complications.

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Joslin Diabetes Center Enrichment Core (tool)

RRID:SCR_015094

Six component core which facilitates the exchange of research information and discussions among investigators, fellows and students within the Joslin Diabetes Center, as well as between Joslin Staff and outside researchers with similar interests.

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SigmaStat (tool)

RRID:SCR_010285

Software tool for data graphing and analysis by Systat Software, Inc.

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ImageQuant (tool)

RRID:SCR_014246

Software for automatic general image analysis. It provides fully automatic analysis of 1-D gels including lane creation, background subtraction, band detection, molecular weight calibration, quantity calibration, and normalization. Editing tools are provided for cropping, rotating, and filtering images.

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SD (tool)

RRID:RGD_70508

Rattus norvegicus with name SD from RGD.

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