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The N-terminus of GalE induces tmRNA activity in Escherichia coli.

PloS one | 2010

The tmRNA quality control system recognizes stalled translation complexes and facilitates ribosome recycling in a process termed 'ribosome rescue'. During ribosome rescue, nascent chains are tagged with the tmRNA-encoded SsrA peptide, which targets tagged proteins for degradation. In Escherichia coli, tmRNA rescues ribosomes arrested on truncated messages, as well as ribosomes that are paused during elongation and termination.

Pubmed ID: 21151867 RIS Download

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Associated grants

  • Agency: NIGMS NIH HHS, United States
    Id: R01 GM078634
  • Agency: NIGMS NIH HHS, United States
    Id: GM078634

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ExPASy Bioinformatics Resource Portal (tool)

RRID:SCR_012880

Portal which provides access to scientific databases and software tools (i.e., resources) in different areas of life sciences including proteomics, genomics, phylogeny, systems biology, population genetics, transcriptomics etc. It contains resources from many different SIB groups as well as external institutions.

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MassLynx (tool)

RRID:SCR_014271

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