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E3 ubiquitin ligase synoviolin is involved in liver fibrogenesis.

PloS one | 2010

Chronic hepatic damage leads to liver fibrosis, which is characterized by the accumulation of collagen-rich extracellular matrix. However, the mechanism by which E3 ubiquitin ligase is involved in collagen synthesis in liver fibrosis is incompletely understood. This study aimed to explore the involvement of the E3 ubiquitin ligase synoviolin (Syno) in liver fibrosis.

Pubmed ID: 21049091 RIS Download

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Associated grants

  • Agency: NIDDK NIH HHS, United States
    Id: R01 DK056621
  • Agency: NIDDK NIH HHS, United States
    Id: R56 DK056621
  • Agency: NIDDK NIH HHS, United States
    Id: DK56621

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