The accumulation of protease resistant conformers of the prion protein (PrP(res)) is a key pathological feature of prion diseases. Polyanions, including RNA and glycosaminoglycans have been identified as factors that contribute to the propagation, transmission and pathogenesis of prion disease. Recent studies have suggested that the contribution of these cofactors to prion propagation may be species specific.
Pubmed ID: 20808809 RIS Download
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View all literature mentionsCell line RK 13 is a Spontaneously immortalized cell line with a species of origin Oryctolagus cuniculus
View all literature mentionsCell line RK 13 is a Spontaneously immortalized cell line with a species of origin Oryctolagus cuniculus
View all literature mentions