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Motesanib inhibits Kit mutations associated with gastrointestinal stromal tumors.

Journal of experimental & clinical cancer research : CR | 2010

Activating mutations in Kit receptor tyrosine kinase or the related platelet-derived growth factor receptor (PDGFR) play an important role in the pathogenesis of gastrointestinal stromal tumors (GIST).

Pubmed ID: 20633291 RIS Download

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C57BL/6J (tool)

RRID:IMSR_JAX:000664

Mus musculus with name C57BL/6J from IMSR.

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