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Medulloblastoma is the most common malignant brain tumour of childhood. The identification of critical genes involved in its pathogenesis will be central to advances in our understanding of its molecular basis, and the development of improved therapeutic approaches.
Pubmed ID: 19584924 RIS Download
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THIS RESOURCE IS NO LONGER IN SERVICE, documented August 22, 2016. A multi-country collaboration among scientists and funding agencies to develop a public resource where genetic similarities and differences in human beings are identified and catalogued. Using this information, researchers will be able to find genes that affect health, disease, and individual responses to medications and environmental factors. All of the information generated by the Project will be released into the public domain. Their goal is to compare the genetic sequences of different individuals to identify chromosomal regions where genetic variants are shared. Public and private organizations in six countries are participating in the International HapMap Project. Data generated by the Project can be downloaded with minimal constraints. HapMap project related data, software, and documentation include: bulk data on genotypes, frequencies, LD data, phasing data, allocated SNPs, recombination rates and hotspots, SNP assays, Perlegen amplicons, raw data, inferred genotypes, and mitochondrial and chrY haplogroups; Generic Genome Browser software; protocols and information on assay design, genotyping and other protocols used in the project; and documentation of samples/individuals and the XML format used in the project.
View all literature mentionsCentral online repository for microRNA nomenclature, sequence data, annotation and target prediction.Collection of published miRNA sequences and annotation.
View all literature mentionsThe Cancer Genome Project is using current high throughput techniques to characterise a series of approximately 800 cancer cell lines including those most frequently used in biological and pharmaceutical research and drug discovery. These screens include sequencing of known cancer genes, copy number and genotyping analysis using SNP arrays and identification of microsatellite instability. Pair-wise comparison of the SNP array data for the entire series of cell lines under study has been performed identifying those lines which, in our set, are either identical or derived from a parental line. These lines are termed synonymous cell lines. Sponsors: This study was supported by the Wellcome Trust and Glaxo Smith Kline. :K eywords: Cancer, Genome, Technique, Research, Pharmaceutical, Drug, Discovery, Gene, Number, Genotype, SNP, Array, Microsatellite, Instability, Biological, Cell line, SNP, Data,
View all literature mentionsFTP site to access Schizosaccharomyces pombe protein data.
View all literature mentionsThe SciCrunch Infrastructure was developed as a cooperative data platform to be used by diverse communities in making data more FAIR.
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