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NKX2-5 regulates the expression of beta-catenin and GATA4 in ventricular myocytes.

PloS one | 2009

The molecular pathway that controls cardiogenesis is temporally and spatially regulated by master transcriptional regulators such as NKX2-5, Isl1, MEF2C, GATA4, and beta-catenin. The interplay between these factors and their downstream targets are not completely understood. Here, we studied regulation of beta-catenin and GATA4 by NKX2-5 in human fetal cardiac myocytes.

Pubmed ID: 19479054 RIS Download

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