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A sensitive retroviral pseudotype assay for influenza H5N1-neutralizing antibodies.

Influenza and other respiratory viruses | 2007

The World Health Organisation (WHO) recommended the development of simple, safe, sensitive and specific neutralization assays for avian influenza antibodies. We have used retroviral pseudotypes bearing influenza H5 hemagglutinin (HA) as safe, surrogate viruses for influenza neutralization assays which can be carried out at Biosafety Level 2.

Pubmed ID: 19453415 RIS Download

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Associated grants

  • Agency: Wellcome Trust, United Kingdom
  • Agency: Medical Research Council, United Kingdom
    Id: G0600369
  • Agency: Medical Research Council, United Kingdom
    Id: G8712499

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HEK293T (tool)

RRID:CVCL_0063

Cell line HEK293T is a Transformed cell line with a species of origin Homo sapiens (Human)

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MDCK (tool)

RRID:CVCL_0422

Cell line MDCK is a Spontaneously immortalized cell line with a species of origin Canis lupus familiaris

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