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Loss of AND-34/BCAR3 expression in mice results in rupture of the adult lens.

Molecular vision | 2009

AND-34/BCAR3 (Breast Cancer Anti-Estrogen Resistance 3) associates with the focal adhesion adaptor protein, p130CAS/BCAR1. Expression of AND-34 regulates epithelial cell growth pattern, motility, and growth factor dependence. We sought to establish the effects of the loss of AND-34 expression in a mammalian organism.

Pubmed ID: 19365570 RIS Download

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Associated grants

  • Agency: NCI NIH HHS, United States
    Id: R01 CA114094

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Covance (tool)

RRID:SCR_001224

A contract research organization providing drug development and animal testing services. Under the name Covance Research Products Inc., based in Denver, Pennsylvania, the company also deals in the import, breeding and sale of laboratory animals. It breeds dogs, rabbits, guinea pigs, non-human primates, and pigs, and runs the largest non-human primate laboratory in Germany. (Wikipedia)

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C57BL/6J (tool)

RRID:IMSR_JAX:000664

Mus musculus with name C57BL/6J from IMSR.

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129S6/SvEvTac (tool)

RRID:MGI:3044417

laboratory mouse with name 129S6/SvEvTac from MGI.

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