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Fibrinogen decreases cardiomyocyte contractility through an ICAM-1-dependent mechanism.

Critical care (London, England) | 2008

Cardiomyocytes exposed to inflammatory processes express intracellular adhesion molecule-1 (ICAM-1). We investigated whether fibrinogen and fibrinogen degradation products, including D-dimer, could alter cardiomyocyte contractile function through interaction with ICAM-1 found on inflamed cardiomyocytes.

Pubmed ID: 18173852 RIS Download

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SD (tool)

RRID:RGD_70508

Rattus norvegicus with name SD from RGD.

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