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Gene expression patterns associated with blood-feeding in the malaria mosquito Anopheles gambiae.

BMC genomics | 2005

Blood feeding, or hematophagy, is a behavior exhibited by female mosquitoes required both for reproduction and for transmission of pathogens. We determined the expression patterns of 3,068 ESTs, representing ~2,000 unique gene transcripts using cDNA microarrays in adult female Anopheles gambiae at selected times during the first two days following blood ingestion, at 5 and 30 min during a 40 minute blood meal and at 0, 1, 3, 5, 12, 16, 24 and 48 hours after completion of the blood meal and compared their expression to transcript levels in mosquitoes with access only to a sugar solution.

Pubmed ID: 15651988 RIS Download

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Associated grants

  • Agency: NIAID NIH HHS, United States
    Id: R01 AI044273
  • Agency: NIAID NIH HHS, United States
    Id: U01 AI048846
  • Agency: NIAID NIH HHS, United States
    Id: R01-AI44273
  • Agency: NIAID NIH HHS, United States
    Id: U01-AI48846

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Jaguar (tool)

RRID:SCR_014895

Ab initio molecular modeling software program that computes an array of molecular properties such as multipole moments, polarizabilities, and electrostatic potential. It can also map reaction coordinates between reactants, products, and transition states.

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