URL: http://www.arpege.cnrs.frCore FacilityArpege
Proper Citation: Arpege Core Facility (RRID:SCR_023092)
Description: Offers functional and structural analysis of protein complexes.Offers possibility to characterize all types of molecular interactions: ligand-target binding, protein-protein interactions, signal transduction, and signalling complexes. Staff members are skilled specialists in luminescence-based techniques and in receptor biology.Application portfolio includes Analysis of cell signalling, by measuring signal transduction;Ligand-target binding (pharmacological analysis, affinity, selectivity); Protein-protein interactions (oligomerization, effectors...); Activation of signalling pathways (G proteins, GRK, arrestins & internalization); Intracellular production of second messengers (cAMP, IP1, Ca2+); Phosphorylation of signalling proteins (ERK, AKT...); Measurement of global cell functions and of different cell parameters (proliferation, migration, invasion...).
Synonyms: Arpege
Resource Type: core facility, service resource, access service resource
Keywords: USEDit, ABRF, functional and structural analysis of protein complexes,
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