Cystic Fibrosis and Pulmonary Diseases Research and Treatment Center Functional Analysis Core (RRID:SCR_015386)Copy Citation Copied
URL: https://www.med.unc.edu/marsicolunginstitute/core-facilities/cftr-functional-analysis-core
Proper Citation: Cystic Fibrosis and Pulmonary Diseases Research and Treatment Center Functional Analysis Core (RRID:SCR_015386)
Description: Core that analyzes ion channel properties and correction efficiency of human bronchial epithelial (HBE) cells from harvested CF lungs to provide a full characterization report to investigators, measures ion transport function of CFTR and ENaC in HBE and human nasal epithelial (HNE) cultures by bioelectric and organoid assays to asses efficacy of candidate therapies, evaluates CFTR expression and processing by biochemical analyses to assess efficacy of CFTR modulation strategies, and validates the suitability of reagents, supplies, and techniques for optimizing HBE and HNE cell integrity.
Resource Type: access service resource, core facility, service resource
Keywords: cystic fibrosis, gene targeting, functional analysis
Funding: Cystic Fibrosis Foundation Resource Development Program BOUCHE15R0
Resource Name: Cystic Fibrosis and Pulmonary Diseases Research and Treatment Center Functional Analysis Core
Resource ID: SCR_015386
Expand Allhas parent organization |
University of North Carolina at Chapel Hill School of Medicine; North Carolina; USA |
has parent organization |
Cystic Fibrosis and Pulmonary Diseases Research and Treatment Center |
is organization facet of |
Cystic Fibrosis and Pulmonary Diseases Research and Treatment Center |
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Source: SciCrunch Registry (RRID:SCR_005400)
Description: Interactive portal for finding and submitting biomedical resources. Resources within SciCrunch have assigned RRIDs which are used to cite resources in scientific manuscripts. SciCrunch Registry, formerly NIF Registry, provides resources catalog. Allows to add new resources. Allows edit existing resources after registration. Curators are tasked with identifying and registering resources, examining data, writing configuration files to index and display data and keeping contents current.
URL: https://rrid.site/rin/sources/SCR_005400
