Predicting Response to Standardized Pediatric Colitis Therapy (PROTECT) (RRID:SCR_014374)Copy Citation Copied
URL: http://www.cscc.unc.edu/protect/
Proper Citation: Predicting Response to Standardized Pediatric Colitis Therapy (PROTECT) (RRID:SCR_014374)
Description: A study of how children newly diagnosed with ulcerative colitis (UC) respond to mesalamine and prednisone (corticosteroid), the standard initial therapies used to treat this disorder. Over a period of 5 years PROTECT will prospectively study the course of 430 children newly diagnosed with UC who are treated with standardized care. Biospecimens (blood, stool, colonic biopsy tissue) will be obtained and used to better understand the effects of genetics, mechanisms of inflammation, Vitamin D, and the bacteria contained in the stool (microbiome) on clinical outcomes.
Abbreviations: PROTECT
Synonyms: Predicting Response to Standardized Pediatric Colitis Therapy
Resource Type: data or information resource, resource, topical portal, portal, data set
Keywords: ulcerative colitis, children, mesalamine, prednisone, genetics, inflammation, vitamin d, clinical outcome
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