Resource Report

URL: http://agem.cnb.csic.es/VisualOmics/aGEM/

Proper Citation: aGEM (RRID:SCR_013349)

Description: Database platform of an integrated view of eight databases (mouse gene expression resources: EMAGE, GXD, GENSAT, BioGPS, ABA, EUREXPRESS; human gene expression databases: HUDSEN, BioGPS and Human Protein Atlas) that allows the experimentalist to retrieve relevant statistical information relating gene expression, anatomical structure (space) and developmental stage (time). Moreover, general biological information from databases such as KEGG, OMIM and MTB is integrated too. It can be queried using gene and anatomical structure. Output information is presented in a friendly format, allowing the user to display expression maps and correlation matrices for a gene or structure during development. An in-depth study of a specific developmental stage is also possible using heatmaps that relate gene expression with anatomical components. This is a powerful tool in the gene expression field that makes easy the access to information related to the anatomical pattern of gene expression in human and mouse, so that it can complement many functional genomics studies. The platform allows the integration of gene expression data with spatial-temporal anatomic data by means of an intuitive and user friendly display.

Abbreviations: aGEM

Synonyms: anatomic Gene Expression Mapping

Resource Type: data or information resource, database

Defining Citation: PMID:22106336

Keywords: gene, anatomy, gene expression, anatomical structure, developmental stage, functional genomics, genomics