URL: http://howard.eagle-i.net/i/00000134-aa20-c323-bf4c-ca4080000000
Proper Citation: Howard Molecular Genetics Core (RRID:SCR_009865)
Description: Core facility that provides the following services: SNP detection service, DNA sequencing service, EBV cell transformation service, DNA sequencer access. The molecular genetics research interests are in human population genetics, anthropological genetics, immunogenetics, and the genetics of complex diseases. Ultimate goals surround elucidating questions of human variation, the evolutionary history of genes within populations and how these gene histories are involved in the etiology of complex diseases. While the laboratory''s research goals have shared consequences for all humanity, specific interests focus on populations of African ancestry. Operational Objectives: 1. Develop a SNP database for mapping functional mutations linked to diseases common in African peoples. 2. Utilization of evolutionary history of candidate genes to identify polymorphisms that are associated with diseases. 3. Exploit the linkage disquilibrium generated by admixture in the African American population for gene mapping.
Resource Type: service resource, access service resource, core facility
Keywords: snp interrogation genotyping, dna sequencing, next generation sequencing, cell immortalization
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