URL: http://www.hsph.harvard.edu/faculty/alkes-price/software/
Proper Citation: LTSOFT (RRID:SCR_009266)
Description: THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 16,2023. A software suite designed to more powerfully leverage clinical-covariates such as age, bmi, smoking status, and gender when conducting case-control association studies. Including these covariates in standard regression models is not only suboptimal, but can in many instances reduce power. LTSOFT employs a liability threshold model approach that takes advantage of known epidemiological results to better model the covariates'' relationship to the phenotype of interest (entry from Genetic Analysis Software)
Abbreviations: LTSOFT
Resource Type: software resource, software application
Keywords: gene, genetic, genomic
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