URL: http://www.sanger.ac.uk/resources/software/ariel/
Proper Citation: ARIEL (RRID:SCR_009126)
Description: Software application that explores the effects of rare variants within complex traits through locus-based analysis. There is increasing evidence that rare variants play a role in some complex traits, but their analysis is not straightforward. Locus-based tests become necessary due to low power in rare variant single-point association analyses. In addition, variant quality scores are available for sequencing data, but are rarely taken into account. To enable this analysis, ARIEL has been developed as a locus-wide regression-based collapsing approach that incorporates variant quality scores. (entry from Genetic Analysis Software)
Abbreviations: ARIEL
Synonyms: Accumulation of Rare variants Integrated and Extended Locus-specific test
Resource Type: software resource, software application
Keywords: gene, genetic, genomic, r, unix, linux
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