URL: http://dmpi.duke.edu/apl-osa-beta-version
Proper Citation: APL-OSA (RRID:SCR_009124)
Description: Software application that in the presence of genetic heterogeneity, can identify a genetically homogenous subset of families based on a trait-related covariate. APL-OSA then tests the relationship between the association statistics (i.e., the APL statistics) calculated based on the subset and the family-specific covariate. APL-OSA is based on the OSA method for linkage and the family-based association test, APL. Thus, APL-OSA has similar properties with OSA and APL. Bi-alleleic markers such as SNPs are accepted by APL-OSA. APL-OSA is a single-marker test and considers one covariate each time. (entry from Genetic Analysis Software)
Abbreviations: APL-OSA
Synonyms: Association in the Presence of Linkage with Ordered Subset Analysis
Resource Type: software application, software resource
Keywords: gene, genetic, genomic, c++, unix, solaris, linux(redhat), ms-windows, xp
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