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Resource Name
RRID:SCR_006293 RRID Copied      
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SHRINE (RRID:SCR_006293)
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Resource Information

URL: https://open.med.harvard.edu/display/SHRINE/Community

Proper Citation: SHRINE (RRID:SCR_006293)

Description: Software providing a scalable query and aggregation mechanism that enables federated queries across many independently operated patient databases. This platform enables clinical researchers to solve the problem of identifying sufficient numbers of patients to include in their studies by querying across distributed hospital electronic medical record systems. Through the use of a federated network protocol, SHRINE allows investigators to see limited data about patients meeting their study criteria without compromising patient privacy. This software should greatly enable population-based research, assessment of potential clinical trials cohorts, and hypothesis formation for followup study by combining the EHR assets across the hospital system. In order to obtain the maximum number of cases representing the study population, it is useful to aggregate patient facts across as many sites as possible. Cutting across institutional boundaries necessitates that each hospital IRB remain in control, and that their local authority is recognized for each and every request for patient data. The independence, ownership, and legal responsibilities of hospitals predetermines a decentralized technical approach, such as a federated query over locally controlled databases. The application comes with the SHRINE Core Ontology but it can be used with any ontology, even one that is disease specific. The Core Ontology is designed to enable the widest range of studies possible using facts gathered in the EMR during routine patient care. SHRINE allows multiple ontologies to be used for different research purposes on the same installed systems.

Abbreviations: SHRINE

Synonyms: Shared Health Research Informatics NEtwork

Resource Type: source code, software application, software resource

Defining Citation: PMID:19567788

Keywords: software network, clinical database, data sharing, clinical, medical record, federated, platform, network

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