URL: http://www.biocomputing.it/digit/index.php
Proper Citation: DIG IT - Database of Immunoglobulins and Integrated Tools (RRID:SCR_005924)
Description: The Database of Immunoglobulins and Integrated Tools (DIG IT) is an integrated resource storing sequences of annotated immunoglobulin variable domains of NCBI database and enriched with tools for searching and analyzing them. It contains 145759 heavy chain sequences and 71404 light chain sequences (47168 kappa type and 24236 lambda type) with assigned canonical structures for the hypervariable loops and the data on the type of antigen as well as the pairing information of immunoglobulin heavy and light chains (9672 total pairs). The user can input the immunoglobulin variable domain sequence (amino acid or nucleotide) of interest (heavy chain variable domain sequence; light chain variable domain sequence or both) to retrieve the closest sequences (sorted according to e-value) with complete annotation. The user can also directly query the database by antigen type, canonical structure, germline family in accordance to the requirements.
Abbreviations: DIG IT, DIGIT
Synonyms: Database of Immunoglobulins and Integrated Tools, DIG IT! Database of Immunoglobulins and Integrated Tools, DIG IT! Database of Immunoglobulins with Integrated Tools, Database of Immunoglobulins Integrated Tools, DIG IT! Integrated Ig Database, DIG IT - Database of Immunoglobulins Integrated Tools
Resource Type: data analysis service, data or information resource, service resource, database, production service resource, analysis service resource
Defining Citation: PMID:22080506
Keywords: sequence, immunoglobulin, variable domain, domain, heavy chain sequence, light chain sequence, antigen type, canonical structure, germline family, blast
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