Resource Report

URL: http://www.genethon.fr/en/rd-2/dna-and-cell-bank/

Proper Citation: Genethon DNA and Cell Bank (RRID:SCR_004639)

Description: Since its creation in 1990, the mission of the Genethon''s DNA and Cell Bank is to promote advances in genetic research by providing the scientific community with a high quality cell and human tissue products resource. Europe''s leading bank for genetic diseases, it serves the whole of the medical and scientific community. Each year, Genethon''s DNA and Cell Bank: * Produces approximately 2,000 lymphoblastoid cell lines * Performs approximately 3,000 DNA extractions * Prepares primary myoblast and fibroblast cultures from approximately 100 biopsies Genethon has developed a computer database for ensuring sample management and traceability, which has been submitted to and approved by the CNIL. The Genethon DNA and Cell Bank has been AFNOR certified, according to French biological research center standard NF S 96-900. The activities of the DNA and Cell Bank are as follows: * Collecting blood or DNA from patients affected with genetic diseases and their families with the minimum identification data necessary for the monitoring and follow-up of samples. * Processing the samples in order to make them available to the scientific community and perpetuating DNA preservation (serum isolation and DNA extraction), isolating lymphocytes and establishing lymphoblastoid B lines and primary cultures (mainly myoblasts and fibroblasts). * Storing samples for future research and preserving the genetic heritage by ensuring the long-term physical security of the preserved samples. * Distributing samples as necessary for ongoing research while complying with the principles and laws of bioethics and using the best available technologies at minimum cost.All these activities are carried out following Standard Operating Procedures (SOP) validated by the Quality Assurance department at Genethon. The Bank is open to researchers in France or abroad wishing to store samples or use the services provided (extraction, establishment of cell lines etc.). Each sample received at Genethon is coded in order to guarantee confidentiality, in accordance with the rules established by the CNIL (French Data Protection Authority). All requests for collaboration with the DNA and Cell Bank should be made in writing to Dr Safaa SAKER-DELYE.

Abbreviations: Genethon DNA and Cell Bank

Synonyms: Genethon DNA Cell Bank

Resource Type: material resource, biomaterial supply resource, cell repository

Keywords: cell, tissue, dna, lymphoblastoid cell line, myoblast, fibroblast, cell line, blood, serum, culture, frozen, dmso, genetic disease, family member, cancer, cardiomyopathy, dermatology, endocrinology, gastroenterology, hematology, chromosomal disease, nephrology, neurology, neuromuscular disease, ophtalmology, ear, nose, throat, psychiatry, rhumatology, rare syndrome