URL: http://www.sanger.ac.uk/resources/software/alien_hunter/
Proper Citation: Alien hunter (RRID:SCR_004575)
Description: Alien_hunter is an application for the prediction of putative Horizontal Gene Transfer (HGT) events with the implementation of Interpolated Variable Order Motifs (IVOMs). This program is free software; you can redistribute it and/or modify it under the terms of the GNU General Public License as published by the Free Software Foundation; either version 2 of the License, or (at your option) any later version. An IVOM approach exploits compositional biases using variable order motif distributions and captures more reliably the local composition of a sequence compared to fixed-order methods. Optionally the predictions can be parsed into a 2-state 2nd order Hidden Markov Model (HMM), in a change-point detection framework, to optimize the localization of the boundaries of the predicted regions. The predictions (embl format) can be automatically loaded into the freely available Artemis genome viewer.
Synonyms: Alien_hunter: Interpolated Variable Order Motifs for Identification of Horizontally Acquired DNA
Resource Type: software application, software resource
Defining Citation: PMID:16837528
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