Resource Report

URL: http://www.orbitoproject.eu/

Proper Citation: ORBITO (RRID:SCR_003876)

Description: Project that aims to increase understanding of how orally-administered drugs are taken up from the gastrointestinal tract into the body, and apply this knowledge to create new laboratory tests and computer models that will better predict the performance of these drugs in patients over a range of clinically relevant conditions. The integration of in vitro and in silico approaches will provide a biopharmaceutics toolkit, validated using clinical data, to accelerate drug development. Ultimately, the project will help to facilitate and speed up the formulation development process and significantly reduce the need for animal experiments in this area as well as for human clinical studies in the future. For patients, the main benefit will be in the form of high quality medicines where the dose required is well calculated and is released in a way that consistently provides an optimal clinical effect.

Abbreviations: ORBITO

Synonyms: orbito - Innovative Tools for Oral Biopharmaceutics, Oral biopharmaceutics tools (ORBITO)

Resource Type: consortium, portal, organization portal, data or information resource

Keywords: drug, drug development, tool development, computer model, drug absorption, oral drug, gastrointestinal tract, clinical, in vivo, in vitro, in silico, biopharmaceutics, dose, drug performance