URL: http://prosite.expasy.org/
Proper Citation: PROSITE (RRID:SCR_003457)
Description: Database of protein families and domains that is based on the observation that, while there is a huge number of different proteins, most of them can be grouped, on the basis of similarities in their sequences, into a limited number of families. Proteins or protein domains belonging to a particular family generally share functional attributes and are derived from a common ancestor. It is complemented by ProRule, a collection of rules based on profiles and patterns, which increases the discriminatory power of profiles and patterns by providing additional information about functionally and/or structurally critical amino acids. ScanProsite finds matches of your protein sequences to PROSITE signatures. PROSITE currently contains patterns and profiles specific for more than a thousand protein families or domains. Each of these signatures comes with documentation providing background information on the structure and function of these proteins. The database is available via FTP.
Abbreviations: PROSITE
Synonyms: PROSITE - Database of protein domains families and functional sites
Resource Type: service resource, analysis service resource, data analysis service, production service resource, data or information resource, database
Defining Citation: PMID:23161676, PMID:19858104, PMID:12230035
Keywords: protein domain, protein family, functional site, protein, structure, function, pattern, profile
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