URL: http://dbm.neuro.uni-jena.de/software/tom/
Proper Citation: Template-O-Matic Toolbox (RRID:SCR_003220)
Description: Software toolbox for creating customized pediatric templates. It provides reference data based on imaging data from the NIH study of normal brain development. Using the general linear model, they statistically isolate the influence of external variables of interest on brain structure, allowing us to generate high-quality matched templates for any given group of subjects. The toolbox offers two options: # to create pediatric templates (T1) and tissue maps (GM, WM, and CSF) based on the objective 1 NIH data (n = 404), in the age range of 5-18 years, or # to assess a new reference population with regard to your variables of interest. Of note, this approach is generally applicable and in no way restricted to analyzing pediatric imaging data: for example, if you aim at investigating the effects of aging in elderly subjects, the toolbox will also allow you to create more appropriate reference (if your group is large enough to isolate such effects).
Abbreviations: TOM Toolbox, TOM
Synonyms: Template-O-Matic
Resource Type: software toolkit, software resource
Defining Citation: PMID:18424084
Keywords: reference, pediatric, neuroimaging, template
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