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Centre for Modeling Human Disease Gene Trap Resource (RRID:SCR_002785)
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Resource Information

URL: http://www.cmhd.ca/genetrap/

Proper Citation: Centre for Modeling Human Disease Gene Trap Resource (RRID:SCR_002785)

Description: Generate gene trap insertions using mutagenic polyA trap vectors, followed by sequence tagging to develop a library of mutagenized ES cells freely available to the scientific community. This library is searchable by sequence or key word searches including gene name or symbol, chromosome location, or Gene Ontology (GO) terms. In addition,they offer a custom email alert service in which researchers are able to submit search criteria. Researchers will receive automated e-mail notification of matching gene trap clones as they are entered into the library and database. The resource features the use of complementary second and third generation polyA trap vectors developed by the Stanford lab and the laboratory of Professor Yasumasa Ishida of the Nara Institute of Science and Technology (NAIST) in Japan to mutagenize murine embryonic stem (ES) cells. CMHD gene trap clones are distributed by the Canadian Mouse Mutant Repository(CMMR). Information about ordering, services, and pricing can be found on their web site (http://www.cmmr.ca/services/index.html).

Abbreviations: CMHD Gene Trap Resource

Synonyms: Centre for Modeling Human Disease (CMHD) Gene Trap Resource

Resource Type: material service resource, service resource, biomaterial manufacture, production service resource

Defining Citation: PMID:14681480

Keywords: embryonic stem cell, polya trap vector, gene trap, insertion, mutagenic polya trap vector, sequence, expression, mutagenesis, gene, mutation, expression profile, phenotype, database, gene expression, vector insertion, expressed sequence tag, blast, clone

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