URL: http://atgc.lbl.gov/atgc/
Proper Citation: Alignable Tight Genomic Cluster (RRID:SCR_001894)
Description: THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 23,2022. ATGC stands for Alignable Tight Genomic Cluster, which is cluster of closely related prokaryotic genomes. ATGC is the principal notion of this web resource. The purpose of this web resource is to prepare ATGC-derived data sets for a variety of research projects in functional and evolutionary genomics. Unique features of ATGC include: * Reliable identification of orthologs (high degree of similarity between the genomes in the set allow an extensive use of synteny in ortholog identification); * Fine granularity of protein classification (in comparisons of more distant genomes, proteins belonging to families of paralogs are often lumped into a singlegroup; under the ATGC approach, comparison of genomic sequences from highly similar genomes allows one to track each set of orthologs separately); * Relative rarity of changes of any kind (in sequence, genome organization and gene content) allows the use of parsimony-related methods of analysis.
Abbreviations: ATGC
Resource Type: data or information resource, database
Defining Citation: PMID:28053163, PMID:18845571
Keywords: gene, genomic cluster, genomic sequence, ortholog, paralog, prokaryotic genomic, protein, protein classification
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