URL: http://www.iro.umontreal.ca/~csuros/quadgt/
Proper Citation: QuadGT (RRID:SCR_000073)
Description: Software package for calling single-nucleotide variants in four sequenced genomes comprising a normal-tumor pair and the two parents. Genotypes are inferred using a joint model of parental variant frequencies, de novo germline mutations, and somatic mutations. The model quantifies the descent-by-modification relationships between the unknown genotypes by using a set of parameters in a Bayesian inference setting. Note that you can use it on any subset of the four related genomes, including parent-offspring trios, and normal-tumor pairs without parental samples.
Abbreviations: QuadGT
Resource Type: software resource
Defining Citation: PMID:23734724
Keywords: single-nucleotide variant, sequenced genome, genotype, genome
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