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University of California at Los Angeles California NanoSystems Institute Advanced Light Microscopy and Spectroscopy Core Facility (RRID:SCR_022789)
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URL: https://alms.cnsi.ucla.edu/become-a-user/

Proper Citation: University of California at Los Angeles California NanoSystems Institute Advanced Light Microscopy and Spectroscopy Core Facility (RRID:SCR_022789)

Description: Offers microscopy services, consultation, and support for application of novel microscopic and spectroscopic methods and advanced image analysis techniques for study of macromolecules, cellular dynamics and nano-scale characterization of bio-materials. Provides collection of customized biological fluorescence microscopes and small-animal imaging devices to study biological processes with high spatial and temporal resolution in whole organisms and in living cells down to single molecule detection level with nanometer accuracy. Located in basement and second floor of CNSI building, two optical suites designed to house microscopes with the required environment control (low vibration, air-filtered, air-conditioned and light-tight) and services. Services include Wide-field Fluorescence Imaging Microscopy (on a limited basis), Confocal One-Photon and Two-Photon Laser Scanning Microscopy, (both point scanning and spinning disk), Fluorescence Correlation Spectroscopy (FCS), Fluorescence Resonance Energy Transfer (FRET), microscopic and macroscopic Fluorescence Lifetime Imaging (FLIM) with Time-Correlated-Single-Photon-Counting (TCSPC) and Near-Infrared (NIR) Detection, Stimulated Emission Depletion laser-scanning microscopy (STED) (a super-resolution technique), both microscopic and macroscopic (small animal) spectral unmixing and laser capture microdissection.

Abbreviations: ALMS

Synonyms: UCLA CNSI Advanced Light Microscopy & Spectroscopy Core, Advanced Light Microscopy & Spectroscopy Core

Resource Type: core facility, access service resource, service resource

Keywords: USEDit, ABRF, Wide-field Fluorescence Imaging Microscopy, Confocal One-Photon and Two-Photon Laser Scanning Microscopy, Fluorescence Correlation Spectroscopy, Fluorescence Resonance Energy Transfer, microscopic and macroscopic Fluorescence Lifetime Imaging, Time-Correlated-Single-Photon-Counting, Near-Infrared Detection, Stimulated Emission Depletion laser-scanning microscopy, microscopic and macroscopic spectral unmixing, laser capture microdissection

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