Memorial Sloan Kettering Cancer Center Molecular Cytogenetics Core Facility (RRID:SCR_017850)Copy Citation Copied
URL: http://www.mskcc.org/research/molecular-cytogenetics
Proper Citation: Memorial Sloan Kettering Cancer Center Molecular Cytogenetics Core Facility (RRID:SCR_017850)
Description: Core supports cytogenetic analysis of cells from human and research animal sources. Range of chromosome analysis techniques are ranging from basic G-banded karyotyping, to 24-color Spectral Karyotyping (SKY), as well as Fluorescence in situ Hybridization (FISH) mapping of cloned DNAs.Services include:Karyotype characterization of new cell lines,Confirmation of cell line identity or stability,Karyotype screening of ES cells prior to transgenesis,Mapping of transgene integration sites,Chromosome or locus copy number enumeration,Publication-quality illustrations.Cytogenetic techniques available:Short-term cell culture,Metaphase chromosome preparation,G-banded karyotyping.FISH techniques available:DNA labeling for custom probe generation (for FISH projects),DNA amplification by DOP-PCR,Chromosome painting,FISH mapping (on chromosomes, interphase nuclei or DNA fibers),Tissue FISH (paraffin or frozen sections),Immuno-FISH (DNA FISH combined with fluorescent immunostaining) , Spectral karyotyping (SKY),Q-FISH (measurement of telomere lengths).
Synonyms: Molecular Cytogenetics
Resource Type: service resource, core facility, access service resource
Keywords: Cytogenetic, analysis, cell, human, animal, chromosome, G-banded, karyotyping, characterization, service, core, ABRF
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