Kansas University at Lawrence Synthetic Chemical Biology Core Facility (RRID:SCR_017750)Copy Citation Copied
URL: https://scb.ku.edu/
Proper Citation: Kansas University at Lawrence Synthetic Chemical Biology Core Facility (RRID:SCR_017750)
Description: Core provides synthetic chemistry expertise. Includes novel and commercially unavailable small molecules, fluorescent molecules and peptides. Assists in identifying hits for medicinal chemistry optimization in infectious disease targets and provides synthesis capabilities for structure activity studies. Core staff will work with investigators to design and synthesis novel molecular probes. Core provides access to model organism Danio rerio (zebrafish), and allows investigators to image embryonic and adult zebrafish treated with molecular probes for phenotypic drug discovery and other projects, encompasses Purification and Analysis Laboratory that provides purification, analysis and quality control of compounds via HPLC-MS, utilizes automated mass directed fractionation for purification in both reversed and normal phases (including chiral separations), provides relative purity analysis by UPLC coupled to high-resolution mass spectrometer for structure confirmation.
Abbreviations: SCB
Synonyms: Synthetic Chemical Biology Core
Resource Type: service resource, core facility, access service resource
Keywords: Synthetic, chemistry, expertise, unavailable, small, molecule, fluorescent, peptide, target, infectious, disease, design, molecular, probe, image, embryonic, adult, zebrafish, phenotyping, drug, discovery, service, core
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