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Kansas University at Lawrence Synthetic Chemical Biology Core Facility (RRID:SCR_017750)
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Resource Information

URL: https://scb.ku.edu/

Proper Citation: Kansas University at Lawrence Synthetic Chemical Biology Core Facility (RRID:SCR_017750)

Description: Core provides synthetic chemistry expertise. Includes novel and commercially unavailable small molecules, fluorescent molecules and peptides. Assists in identifying hits for medicinal chemistry optimization in infectious disease targets and provides synthesis capabilities for structure activity studies. Core staff will work with investigators to design and synthesis novel molecular probes. Core provides access to model organism Danio rerio (zebrafish), and allows investigators to image embryonic and adult zebrafish treated with molecular probes for phenotypic drug discovery and other projects, encompasses Purification and Analysis Laboratory that provides purification, analysis and quality control of compounds via HPLC-MS, utilizes automated mass directed fractionation for purification in both reversed and normal phases (including chiral separations), provides relative purity analysis by UPLC coupled to high-resolution mass spectrometer for structure confirmation.

Abbreviations: SCB

Synonyms: Synthetic Chemical Biology Core

Resource Type: access service resource, core facility, service resource

Keywords: Synthetic, chemistry, expertise, unavailable, small, molecule, fluorescent, peptide, target, infectious, disease, design, molecular, probe, image, embryonic, adult, zebrafish, phenotyping, drug, discovery, service, core

Availability: Open

Resource Name: Kansas University at Lawrence Synthetic Chemical Biology Core Facility

Resource ID: SCR_017750

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Data and Source Information

Source: SciCrunch Registry (RRID:SCR_005400)
Description: Interactive portal for finding and submitting biomedical resources. Resources within SciCrunch have assigned RRIDs which are used to cite resources in scientific manuscripts. SciCrunch Registry, formerly NIF Registry, provides resources catalog. Allows to add new resources. Allows edit existing resources after registration. Curators are tasked with identifying and registering resources, examining data, writing configuration files to index and display data and keeping contents current.
URL: https://rrid.site/rin/sources/SCR_005400