Sanford Burnham Prebys Medical Discovery Institute Functional Genomics Core Facility (RRID:SCR_014859)Copy Citation Copied
URL: https://sbpdiscovery.org/research/shared-resources/functional-genomics/
Proper Citation: Sanford Burnham Prebys Medical Discovery Institute Functional Genomics Core Facility (RRID:SCR_014859)
Description: Core provides the infrastructure for cell-based gain-of-function (ORF, CRISPRa and CRISPRon) and loss-of-functioning (siRN, miRNA, shRNA, CRSIPRko, CRISPRi and CRISPRoff), libraries screening services, starting with assay development and carrying all the way through verification of identified targets. The large scale screens is accomplished via ready-to-use genome-wide or pathway-specific library platforms with choice of arrayed or pooled libraries. The FG core facility is equipped to perform custom CRISPR gene activation, knock-down, knock-out and editing services. We also adopt CRISPR nucleotide base editing technology and offer custom built CRISPR domain libraries. This approach can reveal the specific domain of a target protein interacting with another molecule, such as protein, IncRNA or drug in a native cell cellular environment.
Synonyms: SBP Functional Genomics Core Facility, SBP Medical Discovery Institute Functional Genomics Core Facility
Resource Type: access service resource, core facility, service resource
Keywords: ABRF, genomics services, custom CRISPR gene activation, knock-down, knock-out, editing services,
Availability: Open
Resource Name: Sanford Burnham Prebys Medical Discovery Institute Functional Genomics Core Facility
Resource ID: SCR_014859
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Source: SciCrunch Registry (RRID:SCR_005400)
Description: Interactive portal for finding and submitting biomedical resources. Resources within SciCrunch have assigned RRIDs which are used to cite resources in scientific manuscripts. SciCrunch Registry, formerly NIF Registry, provides resources catalog. Allows to add new resources. Allows edit existing resources after registration. Curators are tasked with identifying and registering resources, examining data, writing configuration files to index and display data and keeping contents current.
URL: https://rrid.site/rin/sources/SCR_005400
