Proper Citation: RHEA (RRID:SCR_004713)
Description: Manually annotated reaction database where all reaction participants (reactants and products) are linked to the ChEBI database (Chemical Entities of Biological Interest) which provides detailed information about structure, formula and charge. Rhea provides built-in validations that ensure both elemental and charge balance of the reactions. The database has been populated with the reactions found in the Enzyme Commission (EC) list (and in the IntEnz and ENZYME databases), extending it with additional known reactions of biological interest. While the main focus of Rhea is enzyme-catalyzed reactions, other biochemical reactions are also included. Rhea is a manually annotated resource and it provides: stable reaction identifiers for each of its reactions; directionality information if the physiological direction of the reaction is known; the possibility to link several reactions together to form overall reactions; extensive cross-references to other resources including enzyme-catalyzed and other metabolic reactions, such as the EC list (in IntEnz), KEGG, MetaCyc and UniPathway; and chemical substructure and similarity searches on compounds in Rhea.
Abbreviations: RHEA
Resource Type: data or information resource, data repository, database, service resource, storage service resource
Defining Citation: PMID:27789701
Keywords: biochemical reaction, reaction, enzyme-catalyzed reaction, spontaneous reaction, enzyme, chemical reaction, gold standard, FASEB list
Funding: Swiss Federal Government SERI ; SystemsX.ch ; Swiss Initiative in Systems Biology ; EMBL ; European Union
Availability: Public, Free, Acknowledgement requested, Available for download, The community can contribute to this resource
Resource Name: RHEA
Resource ID: SCR_004713
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Source: SciCrunch Registry (RRID:SCR_005400)
Description: Interactive portal for finding and submitting biomedical resources. Resources within SciCrunch have assigned RRIDs which are used to cite resources in scientific manuscripts. SciCrunch Registry, formerly NIF Registry, provides resources catalog. Allows to add new resources. Allows edit existing resources after registration. Curators are tasked with identifying and registering resources, examining data, writing configuration files to index and display data and keeping contents current.
URL: https://rrid.site/rin/sources/SCR_005400
