URL: http://mouse.cs.ucla.edu/mousehapmap/
Proper Citation: Mouse HapMap Imputation Genotype Resource (RRID:SCR_002576)
Description: Genetic maps for 94 inbred strains of mouse and imputed genotypes using the NIEHS / Perlegen resequencing resource. Combining with the 13,094 Wellcome Trust SNPs (Single-nucleotide polymorphisms), a set of 132,285 SNPs was compiled and is available for download. Using the mouse HapMap resource, it is possible to accurately impute the genotypes of the 94 strains at the 8 million SNPs discovered by the NIEHS/Perlegen mouse resequencing project. They imputed the genotypes at the NIEHS/Perlegen SNPs from the mouse HapMap SNPs and an additional set of 7,570 gap-filling SNPs provided by NIEHS/Perlegen. Since each NIEHS/Perlegen SNP probe has different quality, they classified roughly half of the SNPs as "high-quality" SNPs, which do not have missing genotype at any of the 15 resequenced strains. The imputed genotypes are available for the high-quality SNPs, which has estimated error rate of 0.27% for high-confidence imputed genotypes. In addition, the imputed genotypes for all 8 million SNPs are also available for download. Their estimated error rate is 0.37% for high-confidence imputed genotypes.
Abbreviations: Mouse HapMap
Resource Type: data or information resource, data set
Keywords: genetic variation, genotype, haplotype, imputed genotype, inbred mouse strain, imputed, phenotype, single-nucleotide polymorphism
Expand Allis related to |
Perlegen/NIEHS National Toxicology: Mouse Genome Resequencing Project |
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