URL: http://cgsc.biology.yale.edu/index.php
Proper Citation: CGSC (RRID:SCR_002303)
Description: The CGSC Collection contains only non-pathogenic BSL-1 laboratory strains, primarily genetic derivatives of Escherichia coli K-12, the laboratory strain widely used in genetic and molecular studies, but a few B strains. The CGSC Database of E. coli genetic information includes genotypes and reference information for the strains in the CGSC collection, the names, synonyms, properties, and map position for genes, gene product information, and information on specific mutations and references to primary literature. The public version of the database includes this information and can be queried directly via this CGSC DB WebServer. The collection includes cultures of wild-type contributed from a number of laboratories and a few thousand derivatives carrying one or up to 29 mutations from among 3500 mutations in (or included in deletions spanning) more than 1300 different loci. Some combinations were constructed particularly for mapping purposes and are still used for teaching and for rapid localization, some for manifestation of a particular phenotype, some strains for transferring a particular region or for complementation analysis. Some plasmids, e.g., the Clarke and Carbon collection, F-primes, a number of toolkit plasmids, and a few classic plasmids are included, but it is not a comprehensive collection of plasmids. Additionally, we have recently acquired most of the strains from the Keio Collection of systematic individual gene knockout (deletion/kan insertion) strains.
Abbreviations: CGSC
Synonyms: The Coli Genetic Stock Center, E. coli Genetic Stock Center, CGSC - The Coli Genetic Stock Center, Coli Genetic Stock Center
Resource Type: biomaterial supply resource, material resource
Keywords: e. coli. escherichia coli, chromosome, culture, genotype, interval, k-12, linkage map, locus, mutation, non-pathogenic, phenotype, plasmid, prokaryote, strain, wild-type, auxotrophic, amino acids, wanner lambda red, gene disruption, keio knockout
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