URL: http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=150520182
Proper Citation: RRID:RRRC_00938
Description: Rattus norvegicus with name LE-ROSA26em1(CAG-tdTomato)Rrrc from RGD.
Species: Rattus norvegicus
Notes: The DNA construct was made by replacing ZsGreen with TdTomato in plasmid pCAG-loxP-STOP-loxP-ZsGreen (Addgene plasmid #51269, donated by Pawel Pelczar). CRISPR/Cas9 genome editing technology was used to knock in the DNA construct into the rat ROSA26 locus in the embryos from outbred BluHsd:LE. Reporter line that can be crossed with Cre-expressing strains. In presence of Cre, the floxed "STOP" upstream of the TdTomato gene is deleted allowing expression of the red fluorescent TdTomato protein. ROSA26 is a synonym for rat Thumpd3-as1 (RGD:6491660) and is used as an official symbol for rat strain nomenclature. Rat Resource and Research Center
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Source: Integrated Animals
Source Database: Rat Resource and Research Center (RRRC)
