URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=30490
Proper Citation: RRID:MMRRC_030490-MU
Description: Mus musculus with name B6;129-Ireb2tm1Roua/Mmmh from MMRRC.
Species: Mus musculus
Notes: Research areas: Hematology, Metabolism, Models for Human Disease, Neurobiology; Mutation Type: Targeted Mutation ; Collection:
Phenotype: kyphosis [MP:0000160]| decreased hematocrit [MP:0000208]| tremors [MP:0000745]| abnormal thalamus morphology [MP:0000832]| abnormal cerebellum morphology [MP:0000849]| Purkinje cell degeneration [MP:0000876]| decreased Purkinje cell number [MP:0000880]| abnormal corpora quadrigemina morphology [MP:0000899]| abnormal locomotor behavior [MP:0001392]| ataxia [MP:0001393]| abnormal gait [MP:0001406]| abnormal posture [MP:0001504]| impaired balance [MP:0001525]| decreased mean corpuscular volume [MP:0002591]| microcytosis [MP:0002813]| decreased hemoglobin content [MP:0002874]| abnormal vestibular system physiology [MP:0004742]| bradykinesia [MP:0005156]| decreased mean corpuscular hemoglobin [MP:0005562]| abnormal iron homeostasis [MP:0005637]| decreased mean corpuscular hemoglobin concentration [MP:0005642]| decreased liver iron level [MP:0008743]| increased liver iron level [MP:0008807]| decreased spleen iron level [MP:0008808]| increased circulating iron level [MP:0008810]| decreased grip strength [MP:0010053]| increased circulating ferritin level [MP:0011890]| decreased circulating unsaturated transferrin level [MP:0011897]| increased brain iron level [MP:0020365]| increased intestinal iron level [MP:0020369]
Affected Gene: Ireb2
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
